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Chapter 3. Genetic Factors

Thomas W. McAllister, M.D.
DOI: 10.1176/appi.books.9781585624201.672184

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Outcome after a traumatic brain injury (TBI) is quite variable and difficult to predict. For example, in clinical practice one can see very different cognitive and functional outcomes in individuals with similar preinjury intellectual and educational backgrounds and seemingly similar degrees of injury. This variability suggests that factors other than injury severity play important roles in outcome. Host genotype might be one such factor.

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